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nf-core/duphold @ 0.0.0-6c4ed3a

SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. This can be used as additional information for filtering variants; for example we will be skeptical of deletion calls that do not have lower than average coverage compared to regions with similar gc-content.

Latest version: 0.0.0-6c4ed3a
Total downloads: 8
Source: nf-core/modules
Authors: @nvnieuwk
Maintainers: @nvnieuwk

Summary

SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. This can be used as additional information for filtering variants; for example we will be skeptical of deletion calls that do not have lower than average coverage compared to regions with similar gc-content.

Get started

Add the following snippet to your workflow script to include this module.

include { DUPHOLD } from 'nf-core/duphold'

License

MIT License

Process
Name DUPHOLD
Input 3 channels
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

alignment_file file

file containing alignments

alignment_index file

index of alignment file

sv_variants file

A variants file containing structural variants

*.{vcf,bcf}(.gz)?
snp_variants file

A variants file containing SNPs

*.{vcf,bcf}(.gz)?
snp_variants_index file

index of snp variants file

fasta file

fasta file

*.{fa,fasta,fna}
fasta_fai file

Index of fasta file

*.fai
Output 2 channels
#1 vcf tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.vcf.gz file

The output VCF

*.vcf.gz
#2 versions_duphold tuple
${task.process} string

The name of the process

duphold string

The name of the tool

duphold -h | sed -e "s/^version: //;q" eval

The expression to obtain the version of the tool

Tool Description Homepage
duphold SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. https://github.com/brentp/duphold
Version 0.0.0-6c4ed3a
Commit ID 6c4ed3a220310b905a1fc9d04f05be2e0837142b
Release Date 23 Apr 2026 15:14:30 (UTC)
Download URL https://registry.nextflow.io/api/v1/modules/nf-core%2Fduphold/0.0.0-6c4ed3a/download
OCI Store URL https://public.cr.seqera.io/v2/nextflow/plugin/modules/nf-core/duphold/blobs/sha256:dafc3edb9dca82010c5c86de095cd7a79ab221aff7508c00ea05cf1334db4f58
Size 2.9 KB
Checksum sha256:dafc3edb9dca82010c5c86de095cd7a79ab221aff7508c00ea05cf1334db4f58
Downloads 3
Version Date Status Downloads Size
0.0.0-6c4ed3a 23 Apr 2026 15:14:30 (UTC) 3 2.9 KB
0.0.0-3fc6d40 22 Apr 2026 15:10:34 (UTC) 3 2.9 KB
0.0.0-0c7146d 08 Apr 2026 18:58:02 (UTC) 2 2.9 KB