×

nf-agent-pi @ 0.5.1

Provider: nextflow-io
Claimed: 20 Aug 2026 12:29:51 (UTC)
Description: The nf-agent-pi plugin enables Nextflow's agent primitive to execute language model calls in containers rather than the driver JVM, providing access to shell and filesystem tools while keeping provider credentials secure through RPC. It integrates with language models (like OpenAI's GPT) and container engines to allow bioinformaticians and data scientists to build AI-powered workflows that can inspect data, call external tools, and process results as native Nextflow tasks.
Latest version: 0.5.1
Total downloads: 0 View trends

Summary

This plugin provides the pi agent runner, one of the two runners that execute the Nextflow agent primitive.

An agent is a process-shaped primitive: it declares typed inputs and outputs, renders a prompt, calls a language model — optionally letting the model call Nextflow modules as tools — and emits the result on a channel. Each invocation runs as an ordinary Nextflow task, so work directories, retries, parallelism, resume, and lineage all apply.

The pi runner executes the agent inside a container rather than in the driver JVM. That container boundary is what makes the shell:bash tool available, which the langchain4j runner (nf-agent) rejects. The plugin itself ships no runtime: the agent harness and the agent-rpc proxy live in a runner image published alongside each Nextflow release, and the plugin jar embeds the coordinate of the image built from the same commit. Provider credentials reach the container over RPC and never enter the task environment, the task script, or the runner's credential store.

Agents are a preview feature. Their syntax and behavior may change in future releases.

Get Started

Select the runner in your nextflow.config:

agent.runner = 'pi'

The plugin is loaded automatically when the configuration declares an agent scope. Declare it explicitly to pin a version:

plugins {
    id 'nf-agent-pi@0.5.1'
}

Provide the model credential, preferably as a pipeline secret:

agent {
    runner = 'pi'
    apiKey = secrets.LLM_KEY
    model = 'openai/gpt-5-mini'
}

A container engine is required, since every agent invocation runs in the runner image.

Examples

A single agent

agent qa {
    model 'openai/gpt-5-mini'
    instruction 'You are a concise scientific assistant.'

    input:
    question: String

    output:
    answer: String

    prompt:
    """
    Answer briefly: ${question}
    """
}

workflow {
    qa('What is FASTQ format?').view()
}

Shell and filesystem tools

shell:bash is supported only on this runner. The runner's file tools are rooted at the work directory with the container as the outer bound; shell:bash has no boundary inside the container:

agent inspector {
    model 'openai/gpt-5-mini'
    tools 'fs:*', 'shell:bash'

    input:
    sample: Path

    output:
    report: String

    prompt:
    """
    Inspect ${sample} and report what kind of data it holds.
    """
}

Pinning the runner image

By default the runner uses the image published with the Nextflow release it ships in. Override it to run a mirrored or custom image:

agent {
    runner = 'pi'
    container = 'public.cr.seqera.io/nextflow/nf-agent-pi:0.5.1'
}

Reaching the driver from the container

Tool calls travel back to the driver over RPC. The driver host is inferred where possible; override it when the inferred address is not reachable from the container:

agent {
    runner = 'pi'
    rpc {
        remoteHost = '10.0.1.7'
        port = 8099
    }
}

License

Apache License 2.0

Nextflow version >=26.08.0-edge
Depends On -
Release Date 20 Aug 2026 12:53:17 (UTC)
Release Notes -
Download URL https://registry.nextflow.io/api/v1/plugins/nf-agent-pi/0.5.1/download/nf-agent-pi-0.5.1.zip
Store URL https://public.cr.seqera.io/v2/nextflow/plugin/nf-agent-pi/blobs/sha256:c21dc49fac0699b8c14fa5e48425997e742ace3ccb8b26debf4e9cd109c2d32b
Size 22.5 MB
Checksum b5f1060c42c1ad17311d369e14ce795b5bddf42deb08592723db1e081a8f305e7f5b690cdb6638fb06cb326f6c3bffa5b29bee835e4a362ed0bc082dd4749d46
Total downloads 0 View trends
Security Scan
Version Nextflow version Date Status Downloads
0.5.1 >=26.08.0-edge 20 Aug 2026 12:53:17 (UTC) 0