nf-biofuse / Download Trends
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Description:
nf-biofuse serves a VCF Zarr (VCZ) store to a Nextflow run as an ordinary PLINK 1 BED/BIM/FAM trio, using BioFuse to mount the store as virtual files, so no PLINK copy of the cohort is written to disk.
Key features:
- Mounts the store when the run starts and unmounts it on every exit path (completion, failure, Ctrl-C, SIGTERM, SIGKILL), with stale-mount reclaim
- Writes a cohort manifest from a user template, so any pipeline that reads PLINK 1 files can use the mount without code changes
- Declares a content-addressed view identity, so pipelines such as nf-core/gwas can skip re-hashing the genotypes and -resume stays cached
- Supports vcztools selection options (regions, samples, allele filters); readahead tuning for concurrent tasks
This benefits the Nextflow community by letting pipelines analyse biobank-scale VCZ cohorts with PLINK-based tools without duplicating terabytes of genotype data.
License: Apache 2.0