Description:`nf-drs` is a Nextflow plugin that integrates with GA4GH DRS-compliant data repositories (Gen3 commons like NCI CRDC, AnVIL, and BioData Catalyst) to enable transparent access to remote data objects using `drs://` URIs in workflows. It automatically resolves DRS identifiers to presigned URLs and streams the data, supporting pluggable authentication methods including Gen3 API keys and OAuth2 bearer tokens. Bioinformaticians and researchers can now reference controlled-access or public genomic data directly in Nextflow pipelines without manual URL resolution or special syntax.