Description:This Nextflow plugin integrates with Synapse (Sage Bionetworks) to enable transparent reading and writing of files using `syn://` URIs directly in pipelines, solving the problem of accessing cloud-hosted research data without manual downloads. It supports versioned files, secure authentication, and samplesheet integration, making it ideal for bioinformaticians and researchers running nf-core pipelines that need to work with Synapse-hosted datasets.