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nf-core/plink/indeppairwise @ 0.0.0-0c7146d

Produce a pruned subset of markers that are in approximate linkage equilibrium with each other. Pairs of variants in the current window with squared correlation greater than the threshold are noted and variants are greedily pruned from the window until no such pairs remain.

Latest version: 0.0.0-6c4ed3a
Total downloads: 9
Source: nf-core/modules
Authors: @atrigila
Maintainers: @atrigila

Summary

Produce a pruned subset of markers that are in approximate linkage equilibrium with each other. Pairs of variants in the current window with squared correlation greater than the threshold are noted and variants are greedily pruned from the window until no such pairs remain.

Get started

Add the following snippet to your workflow script to include this module.

include { PLINK_INDEPPAIRWISE } from 'nf-core/plink/indeppairwise'

License

MIT License

Process
Name PLINK_INDEPPAIRWISE
Input 4 channels
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

bed file

PLINK binary biallelic genotype table file

*.{bed}
bim file

PLINK extended MAP file

*.{bim}
fam file

PLINK sample information file

*.{fam}
window_size string

Window size in variant count or kilobase (if the 'kb' modifier is present) units, a variant count to shift the window at the end of each step, and a variance inflation factor (VIF) threshold.

variant_count string

Variant count to shift the window at the end of each step.

r2_threshold string

Pairwise r2 threshold. At each step, pairs of variants in the current window with squared correlation greater than the threshold are noted, and variants are greedily pruned from the window until no such pairs remain

Output 3 channels
#1 prunein tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.prune.in file

File with IDs of pruned subset of markers that are in approximate linkage equilibrium with each other

*.{prune.in}
#2 pruneout tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.prune.out file

File with IDs of excluded variants

*.{prune.out}
#3 versions_plink tuple
${task.process} string

The name of the process

plink string

The name of the tool

plink --version 2>&1 | sed 's/^PLINK v//;s/ .*//' eval

The expression to obtain the version of the tool

Tool Description Homepage
plink Whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner. https://www.cog-genomics.org/plink
Version 0.0.0-0c7146d
Commit ID 6c4ed3a220310b905a1fc9d04f05be2e0837142b
Release Date 08 Apr 2026 19:27:32 (UTC)
Download URL https://registry.nextflow.io/api/v1/modules/nf-core%2Fplink%2Findeppairwise/0.0.0-0c7146d/download
OCI Store URL https://public.cr.seqera.io/v2/nextflow/plugin/modules/nf-core/plink/indeppairwise/blobs/sha256:05fd897f5656316552e791768f9e2115a36e377ee4ce86d52e849e701c426167
Size 3.0 KB
Checksum sha256:05fd897f5656316552e791768f9e2115a36e377ee4ce86d52e849e701c426167
Downloads 3
Version Date Status Downloads Size
0.0.0-6c4ed3a 23 Apr 2026 15:37:50 (UTC) 3 3.0 KB
0.0.0-3fc6d40 22 Apr 2026 15:26:57 (UTC) 3 3.1 KB
0.0.0-0c7146d 08 Apr 2026 19:27:32 (UTC) 3 3.0 KB