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nf-core/sentieon/tnscope @ 0.0.0-6c4ed3a

TNscope algorithm performs somatic variant calling on the tumor-normal matched pair or the tumor only data, using a Haplotyper algorithm.

Latest version: 0.0.0-6c4ed3a
Total downloads: 6
Source: nf-core/modules
Authors: @ramprasadn
Maintainers: @ramprasadn

Summary

TNscope algorithm performs somatic variant calling on the tumor-normal matched pair or the tumor only data, using a Haplotyper algorithm.

Get started

Add the following snippet to your workflow script to include this module.

include { SENTIEON_TNSCOPE } from 'nf-core/sentieon/tnscope'

License

MIT License

Process
Name SENTIEON_TNSCOPE
Input 9 channels
#1 tuple
meta map

Groovy Map containing sample information. e.g. [ id:'test' ]

input file

One or more BAM or CRAM files.

*.{bam,cram}
input_index file

Indices for the input files

*.{bai,crai}
intervals file

bed or interval_list file containing interval in the reference that will be used in the analysis. Only recommended for large WGS data, else the overhead may not be worth the additional parallelisation.

*.{bed,interval_list}
#2 tuple
meta2 map

Groovy Map containing reference information. e.g. [ id:'test' ]

fasta file

Genome fasta file

*.{fa,fasta}
#3 tuple
meta3 map

Groovy Map containing reference information. e.g. [ id:'test' ]

fai file

Index of the genome fasta file

*.fai
#4 tuple
meta4 map

Groovy Map containing reference information. e.g. [ id:'test' ]

dbsnp file

Single Nucleotide Polymorphism database (dbSNP) file

*.vcf.gz
#5 tuple
meta5 map

Groovy Map containing reference information. e.g. [ id:'test' ]

dbsnp_tbi file

Index of the Single Nucleotide Polymorphism database (dbSNP) file

*.vcf.gz.tbi
#6 tuple
meta6 map

Groovy Map containing reference information. e.g. [ id:'test' ]

pon file

Single Nucleotide Polymorphism database (dbSNP) file

*.vcf.gz
#7 tuple
meta7 map

Groovy Map containing reference information. e.g. [ id:'test' ]

pon_tbi file

Index of the Single Nucleotide Polymorphism database (dbSNP) file

*.vcf.gz.tbi
#8 tuple
meta8 map

Groovy Map containing reference information. e.g. [ id:'test' ]

cosmic file

Catalogue of Somatic Mutations in Cancer (COSMIC) VCF file.

*.vcf.gz
#9 tuple
meta9 map

Groovy Map containing reference information. e.g. [ id:'test' ]

cosmic_tbi file

Index of the Catalogue of Somatic Mutations in Cancer (COSMIC) VCF file.

*.vcf.gz.tbi
Output 3 channels
#1 vcf tuple
meta map

Groovy Map containing reference information. e.g. [ id:'test' ]

*.vcf.gz file

VCF file

*.{vcf.gz}
#2 index tuple
meta map

Groovy Map containing reference information. e.g. [ id:'test' ]

*.vcf.gz.tbi file

Index of the VCF file

*.vcf.gz.tbi
#3 versions_sentieon tuple
${task.process} string

The process the versions were collected from

sentieon