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Showing module(s) with keyword "sentieon"

Module Keywords Description
nf-core/sentieon/applyvarcal sentieon applyvarcal varcal VQSR Apply a score cutoff to filter variants based on a recalibration table. Sentieon's Aplyvarcal performs the second pass in a two-stage process called Variant Quality Score Recalibration (VQSR). Specifically, it applies filtering to the input variants based on the recalibration table produced in the previous step VarCal and a target sensitivity value. https://support.sentieon.com/manual/usages/general/#applyvarcal-algorithm
nf-core/sentieon/bwaindex index fasta genome reference sentieon Create BWA index for reference genome
nf-core/sentieon/bwamem mem bwa alignment map fastq bam sentieon Performs fastq alignment to a fasta reference using Sentieon's BWA MEM
nf-core/sentieon/collectvcmetrics vcf sentieon genomics Accelerated implementation of the Picard CollectVariantCallingMetrics tool.
nf-core/sentieon/coveragemetrics coverage sentieon genomics Accelerated implementation of the GATK DepthOfCoverage tool.
nf-core/sentieon/datametrics metrics bam sentieon Collects multiple quality metrics from a bam file
nf-core/sentieon/dedup mem dedup map bam cram sentieon Runs the sentieon tool LocusCollector followed by Dedup. LocusCollector collects read information that is used by Dedup which in turn marks or removes duplicate reads.
nf-core/sentieon/dnamodelapply dnamodelapply vcf filter sentieon modifies the input VCF file by adding the MLrejected FILTER to the variants
nf-core/sentieon/dnascope dnascope sentieon variant_calling DNAscope algorithm performs an improved version of Haplotype variant calling.
nf-core/sentieon/haplotyper sentieon haplotypecaller haplotype Runs Sentieon's haplotyper for germline variant calling.
nf-core/sentieon/hsmetrics metrics bam sentieon Collects hybrid-selection (HS) metrics for a SAM or BAM file.
nf-core/sentieon/qualcal base quality score recalibration bqsr sentieon Generate recalibration table and optionally perform base quality recalibration
nf-core/sentieon/readwriter merge convert readwriter sentieon Merges BAM files, and/or convert them into cram files. Also, outputs the result of applying the Base Quality Score Recalibration to a file.
nf-core/sentieon/rsemcalculateexpression rsem expression quantification sentieon Calculate expression with RSEM
nf-core/sentieon/rsempreparereference rsem genome index sentieon Prepare a reference genome for RSEM
nf-core/sentieon/tnfilter tnfilter filter sentieon tnhaplotyper2 vcf Filters the raw output of sentieon/tnhaplotyper2.
nf-core/sentieon/tnhaplotyper2 tnseq tnhaplotyper2 sentieon variant_calling Tnhaplotyper2 performs somatic variant calling on the tumor-normal matched pairs.
nf-core/sentieon/tnscope tnscope sentieon variant_calling TNscope algorithm performs somatic variant calling on the tumor-normal matched pair or the tumor only data, using a Haplotyper algorithm.
nf-core/sentieon/varcal sentieon varcal variant recalibration Module for Sentieons VarCal. The VarCal algorithm calculates the Variant Quality Score Recalibration (VQSR). VarCal builds a recalibration model for scoring variant quality. https://support.sentieon.com/manual/usages/general/#varcal-algorithm
nf-core/sentieon/wgsmetrics metrics bam sentieon Collects whole genome quality metrics from a bam file