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nf-core/viennarna/rnacofold @ 0.0.0-3fc6d40

calculate secondary structures of two RNAs with dimerization

Latest version: 0.0.0-6c4ed3a
Total downloads: 9
Source: nf-core/modules
Authors: @kokul-atx
Maintainers: @kokul-atx

Summary

calculate secondary structures of two RNAs with dimerization

Get started

Add the following snippet to your workflow script to include this module.

include { VIENNARNA_RNACOFOLD } from 'nf-core/viennarna/rnacofold'

License

MIT License

Process
Name VIENNARNA_RNACOFOLD
Input 1 channel
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

rnacofold_fasta file

A fasta file containing RNA or transcript sequences

*.{fasta,fa}
Output 3 channels
#1 versions
versions.yml file

File containing software versions

versions.yml
#2 rnacofold_ps tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.ps file

The text Output of RNAfold that contains the predicted secondary structure in postscript format

*.{ps}
#3 rnacofold_csv tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.csv file

The CSV Output of RNAcofold that has the predicted structure and energies

*.{csv}
Tool Description Homepage
viennarna calculate secondary structures of two RNAs with dimerization The program works much like RNAfold, but allows one to specify two RNA sequences which are then allowed to form a dimer structure. RNA sequences are read from stdin in the usual format, i.e. each line of input corresponds to one sequence, except for lines starting with > which contain the name of the next sequence. To compute the hybrid structure of two molecules, the two sequences must be concatenated using the & character as separator. RNAcofold can compute minimum free energy (mfe) structures, as well as partition function (pf) and base pairing probability matrix (using the -p switch) Since dimer formation is concentration dependent, RNAcofold can be used to compute equilibrium concentrations for all five monomer and (homo/hetero)-dimer species, given input concentrations for the monomers. Output consists of the mfe structure in bracket notation as well as PostScript structure plots and “dot plot” files containing the pair probabilities, see the RNAfold man page for details. In the dot plots a cross marks the chain break between the two concatenated sequences. The program will continue to read new sequences until a line consisting of the single character @ or an end of file condition is encountered. https://www.tbi.univie.ac.at/RNA/
Version 0.0.0-3fc6d40
Commit ID 6c4ed3a220310b905a1fc9d04f05be2e0837142b
Release Date 22 Apr 2026 15:36:22 (UTC)
Download URL https://registry.nextflow.io/api/v1/modules/nf-core%2Fviennarna%2Frnacofold/0.0.0-3fc6d40/download
OCI Store URL https://public.cr.seqera.io/v2/nextflow/plugin/modules/nf-core/viennarna/rnacofold/blobs/sha256:c3605e6a50df9892ce53339549c8df3c719683d2f3f851441cf87bd51d3d3355
Size 2.9 KB
Checksum sha256:c3605e6a50df9892ce53339549c8df3c719683d2f3f851441cf87bd51d3d3355
Downloads 3
Version Date Status Downloads Size
0.0.0-6c4ed3a 23 Apr 2026 15:52:32 (UTC) 3 2.9 KB
0.0.0-3fc6d40 22 Apr 2026 15:36:22 (UTC) 3 2.9 KB
0.0.0-0c7146d 08 Apr 2026 19:46:53 (UTC) 3 2.9 KB