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nf-core/cadd @ 0.0.0-0c7146d

CADD is a tool for scoring the deleteriousness of single nucleotide variants as well as insertion/deletions variants in the human genome.

Latest version: 0.0.0-0c7146d
Total downloads: 4
Source: nf-core/modules
Authors: @ramprasadn
Maintainers: @ramprasadn

Summary

CADD is a tool for scoring the deleteriousness of single nucleotide variants as well as insertion/deletions variants in the human genome.

Get started

Add the following snippet to your workflow script to include this module.

include { CADD } from 'nf-core/cadd'

License

MIT License

Process
Name CADD
Input 3 channels
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

vcf file

Input file for annotation in vcf or vcf.gz format

*.{vcf,vcf.gz}
#2 tuple
meta2 map

Groovy Map containing reference information e.g. [ id:'test' ]

annotation_dir directory

Path to folder containing the vcf files with precomputed CADD scores. This folder contains the uncompressed files that would otherwise be in data/annotation folder as described in https://github.com/kircherlab/CADD-scripts/#manual-installation.

#3 tuple
meta3 map

Groovy Map containing reference information e.g. [ id:'test' ]

prescored_dir directory

Path to folder containing prescored CADD score files. Expected structure mirrors data/prescored/ from the CADD-scripts installation: <prescored_dir>/ GRCh38_v1.7/ incl_anno/ # *.tsv.gz + *.tsv.gz.tbi (scores with annotations) no_anno/ # *.tsv.gz + *.tsv.gz.tbi (scores only) GRCh37_v1.7/ incl_anno/ no_anno/ See https://github.com/kircherlab/CADD-scripts/#manual-installation for details.

Output 2 channels
#1 tsv tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

${prefix}.tsv.gz file

Annotated tsv file

*.{tsv,tsv.gz}
#2 versions_cadd tuple
${task.process} string

The name of the process

cadd string

The name of the tool

1.7.3 string

The expression to obtain the version of the tool

Tool Description Homepage
cadd CADD scripts release for offline scoring https://cadd.gs.washington.edu/
Version 0.0.0-0c7146d
Commit ID 0c7146d85582628b5d1034504702fa808632b1af
Release Date 08 Apr 2026 18:50:11 (UTC)
Download URL https://registry.nextflow.io/api/v1/modules/nf-core%2Fcadd/0.0.0-0c7146d/download
OCI Store URL https://public.cr.seqera.io/v2/nextflow/plugin/modules/nf-core/cadd/blobs/sha256:973eabd71990a1ff5128bd385dff38c17dd45f310686fdd54bd90cc45303fd06
Size 2.8 KB
Checksum sha256:973eabd71990a1ff5128bd385dff38c17dd45f310686fdd54bd90cc45303fd06
Downloads 4
Version Date Status Downloads Size
0.0.0-0c7146d 08 Apr 2026 18:50:11 (UTC) 4 2.8 KB